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Multiple myeloma (MM) is usually found in patients (pts) over the age of 65. A very small number of pts is detected before the age of 40 (~2%) or under the age of 30 (~0.3%). Because of the low incidence of early-onset MM there is limited data regarding the clinicopathology and prognosis of the disease in the young population.
Artur Jurczyszyn from the Department of Hematology, Jagiellonian University Medical College, Cracow, Poland, and colleagues in a study in the journal Leukemia and Lymphoma present data of a retrospective study of a cohort of young MM patients ≤ 30 years of age. The analysis included 52 pts; 47 diagnosed after 2006 and 5 diagnosed between 1989−2006. This is the first study in the era of novel agents that focuses exclusively on MM pts up to the age of 30.
This study reveals that 30-year-old or younger MM pts show similar and possibly better responses to treatment than those of older pts. However, none of the parameters analyzed revealed a correlation with OS rates, underlying that at the moment there are no prognostic markers for younger MM pts.
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